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Emergency Medical Minute


Nov 30, 2021

Contributor: Nick Hatch, MD

Educational Pearls:

  • Inhaled nitric oxide or Flolan may be considered in COVID
    • Flolan is a prostaglandin can be inhaled or given IV
  • These medications are classically used for right-sided heart failure, but may be used in COVID
  • Causes pulmonary vasodilation to reduce the resistance against the right ventricle
  • Complications include hypotension and hemolysis, but nitric oxide can be turned off very quickly if needed
    • Be careful and wean patients on nitric oxide for pulmonary hypertension


Lotz C, Muellenbach RM, Meybohm P, et al. Effects of inhaled nitric oxide in COVID-19-induced ARDS - Is it worthwhile?. Acta Anaesthesiol Scand. 2021;65(5):629-632. doi:10.1111/aas.13757

Summarized by John Spartz, MS4 | Edited by Erik Verzemnieks, MD


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