Nov 30, 2021
Contributor: Nick Hatch, MD
Educational Pearls:
- Inhaled nitric oxide or Flolan may be considered in COVID
-
- Flolan is a prostaglandin can be inhaled or given IV
- These medications are classically used for right-sided heart failure, but may be used in COVID
- Causes pulmonary vasodilation to reduce the resistance against...
Nov 23, 2021
Educational Pearls:
- Organophosphates affect the cholinergic system by inhibiting acetylcholinesterase affecting muscarinic and nicotinic receptors
- Symptoms include lacrimation, salivation, bronchoconstriction, blurred vision, bradycardia, bronchorrhea, emesis, and diarrhea
- Initially, the patient should be...
Nov 22, 2021
Contributor: Chris Holmes, MD
Educational Pearls:
- Parkland Formula: 4 mL x [Total Body Surface Area Burned (%)] x [body weight (kg)] given in 24 hours
-
- 50% given over 8 hours and 50% given over the next 16 hours
- Brooke Formula: 2 mL x [Total Body Surface Area Burned (%)] x [body weight (kg)] given in 24 hours
-
- 50%...
Nov 16, 2021
Educational Pearls:
- Recent updates to treatment guidelines increased the 250 mg ceftriaxone IM dose to 500 mg ceftriaxone IM
- IM dosing can be very painful, so other methods of administration can help decrease pain for patients
- Using IV ceftriaxone instead of IM has no significant difference in pharmacokinetics or...
Nov 15, 2021
Contributor: Jared Scott, MD
Educational Pearls:
- A press release from Merck introduced Molnupiravir for treatment of mild to moderate COVID-19
- The yet to be published study is a randomized control trial at around 100 different sites
- Reported outcomes were hospitalization and mortality from COVID and mortality from...