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Emergency Medical Minute

 

Jul 24, 2019

Educational Pearls:

  • Buprenorphine is a semi-synthetic derivative of the opium poppy
  • FDA approved for the treatment of opiate use disorder and chronic pain
  • Benefit in emergency department use is the ceiling effect - producing less euphoria as well as respiratory depression with higher doses 
  • It has an onset of 30-60...


Jul 4, 2019

Contributor: Charleen Gnisci, PharmD

Educational Pearls:

  • Causes of increased intracranial pressure may include intracranial hemorrhage, malignancy, and trauma. 
  • While definite treatment is to remove the offending cause, there are emergency medicine  
  • Non-pharmacologic methods include elevating head of bed and removing...


May 17, 2019

Author: Jared Scott, MD

Educational Pearls:

  • Ondansetron (Zofran) is one of the latest drugs that has had concerns raised about side effects, particularly in pregnancy
  • 2018 study probed two birth defect databases to assess increases in 51 major birth defects with increased exposure to ondansetron
  • Only two of the 51 had...


Apr 17, 2019

Author: Nick Hatch, MD

Educational Pearls:

 

  • A recent study investigated the effect of scheduled IV acetaminophen on the incidence of delirium in post-CABG patients in the ICU
  • The use of scheduled IV acetaminophen reduced the rate of delirium in these patients compared to placebo
  • This may be due to the analgesic effect...


Mar 29, 2019

Author: Don Stader, MD

Educational Pearls:

  • Non-steroidal anti-inflammatory drugs (NSAIDs) are effective pain relievers but come with important side effects
  • NSAIDs inhibit COX-1 and/or COX-2, which decreases the production of prostaglandins, which reduce pain and inflammation
  • Side effects of NSAIDS include increased...