Primary syphilis: frequently overlooked because initial chancre
is painless.
Secondary syphilis: viral syndrome, rash on trunk, palms, and
soles.
Latent syphilis: asymptomatic period, lasting 5-20 years.
Tertiary syphilis: includes neurosyphilis (dementia,
encephalitis, etc.) and cardiovascular syphilis (aortitis,
etc).
Treatment penicillin G 2.4 million units once for primary or
secondary treatment; once weekly for 3 weeks for
latent/tertiary.
References
Mattei, P., Beachkofsky, T., Gilson, R., Wisco, O.
Syphilis: A reemerging infection. 2012.American Family Physician.,86(5), 433-440.
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