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Emergency Medical Minute


Feb 15, 2021

Contributor: Peter Bakes , MD

Educational Pearls:

  • Pediatric Fever + Rash Differential: scarlet fever, measles, rubella, chicken pox, fifth’s disease, HHV-6, adenovirus, anaphylaxis, Kawasaki’s disease
  • Kawasaki’s is diagnosed clinically with prolonged fever (>7 days fever in <6 months > 5 days of fever >6 months with 4 of the following: 
    • Strawberry tongue/fissured lips
    • Bilateral conjunctival injection
    • Cervical lymphadenopathy
    • Hand/foot edema
    • Maculopapular rash
  • Can develop life threatening coronary artery aneurysms
  • Treated with aspirin/IVIG


Modesti AM, Plewa MC. Kawasaki Disease. [Updated 2020 Jul 2]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2020 Jan-. Available from:

Ramphul K, Mejias SG. Kawasaki disease: a comprehensive review. Arch Med Sci Atheroscler Dis. 2018;3:e41-e45. Published 2018 Mar 21. doi:10.5114/amsad.2018.74522

Summarized by John Spartz, MS3 | Edited by Erik Verzemnieks, MD