Nov 23, 2021
Educational Pearls:
- Organophosphates affect the cholinergic system by inhibiting acetylcholinesterase affecting muscarinic and nicotinic receptors
- Symptoms include lacrimation, salivation, bronchoconstriction, blurred vision, bradycardia, bronchorrhea, emesis, and diarrhea
- Initially, the patient should be...
Nov 22, 2021
Contributor: Chris Holmes, MD
Educational Pearls:
- Parkland Formula: 4 mL x [Total Body Surface Area Burned (%)] x [body weight (kg)] given in 24 hours
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- 50% given over 8 hours and 50% given over the next 16 hours
- Brooke Formula: 2 mL x [Total Body Surface Area Burned (%)] x [body weight (kg)] given in 24 hours
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- 50%...
Nov 16, 2021
Educational Pearls:
- Recent updates to treatment guidelines increased the 250 mg ceftriaxone IM dose to 500 mg ceftriaxone IM
- IM dosing can be very painful, so other methods of administration can help decrease pain for patients
- Using IV ceftriaxone instead of IM has no significant difference in pharmacokinetics or...
Nov 15, 2021
Contributor: Jared Scott, MD
Educational Pearls:
- A press release from Merck introduced Molnupiravir for treatment of mild to moderate COVID-19
- The yet to be published study is a randomized control trial at around 100 different sites
- Reported outcomes were hospitalization and mortality from COVID and mortality from...
Nov 9, 2021
Contributor: Nick Tsipis, MD
Educational Pearls:
- Meaningful survival under 10% for out of hospital cardiac arrest
- The most common cause of out-of-hospital cardiac arrest is due to cardiac ischemia
- Study looked at whether taking patients without ST elevation who had an out-of-hospital cardiac arrest with return of...